Biology: Model Systems in Neuroscience

Provides students a deeper level of scientific fluency with guidance on how to critically read and understand primary scientific literature and how to communicate those findings, using model systems as our guide. Prerequisites: BCOR 2300 and (BCOR 2500 or NSCI 2105).

Prereqs enforced by the system: BCOR 2300 and (BCOR 2500 or NSCI 2105); PACE students with permission and override

This course explores how model systems are used to investigate questions in neuroscience research. We will discuss the rationale behind choosing model organisms, the limitations of different model systems, and how they contribute to discoveries about neural function, behavior, and disease. Students will learn about model systems through a combination of lecture and student-led research, emphasizing the development of scientific fluency in critical reading of literature, communicating scientific findings, and the writing of research proposals. Some topics covered include genetic manipulation, cell and molecular biology, anatomy, neuronal structure and function, behavior, and disease, and will also be tailored to student interest. 1. Learn about a variety of model organisms used in neuroscience and biological research. 2. Navigate both the core concepts and specific details of various scientific methods. 3. Strengthen fluency in the reading, writing, and presentation of scientific articles. 4. Take a critical lens to scientific papers, especially in discussing the strengths and weaknesses of various model systems used in neuroscience. Students should expect to spend approximately 4-5 hours per week outside of class on reading and analyzing primary scientific literature, preparing presentations, writing assignments, etc.. For the neuroscience curriculum, this course is considered a category B: Cellular/Molecular elective.

This class will feature in-person instructor-led lecture covering various aspects of model systems and research techniques, a series of guest lectures showcasing neuroscience research at UVM, student group presentations on research papers, and the writing of individual mini grant proposals. There is no required textbook for this course; however, readings will be assigned and posted on Brightspace. There may be occasional visits to lab spaces.

Grades are based on in-class attendance, participation in discussions, application question worksheets, article reflection worksheets, journal presentations, and a mini grant proposal assignment with a peer review processes.