Bill was trained as a clinical psychologist at the University of Vermont and then completed a postdoctoral fellowship in psychiatric epidemiology at Duke University Medical Center. As part of a NIMH K23 award and a NARSAD early-career investigator award, he received supplemental training in psychiatric genetics and biomarker analysis. Since then, Bill has been the PI or Co-I on grants from NIMH, NIDA, NICHD and the Brain & Behavior Research Foundation to support my work on the longitudinal, representative Great Smoky Mountains Study. He also is an investigator on the Duke Preschool Anxiety Study, the Fast Track Intervention Trial, the University of Vermont Wellness Study, and Project RAISE. Across all of these studies, his research program has focused on understanding the development of emotional and behavior health across the lifespan. This work includes understanding the interplay between early adverse experiences and genetic vulnerability with other individual, family, and contextual characteristics. The program of research has led to over 100 peer-reviewed manuscripts including publications in JAMA, JAMA: Pediatrics, JAMA: Psychiatry, the American Journal of Psychiatry, American Journal of Public Health, Biological Psychiatry, Molecular Psychiatry, and the Proceedings of the National Academy of Sciences.